Assisted Reproduction and Testing Positive for COVID-19

Assisted Reproduction and Testing Positive for COVID-19

This episode covers several recent studies, with summary tables and relevant resources provided below, on infertile women using assisted reproductive technology (ART) after testing positive for COVID-19.

Episode Timestamps:

  • 1:49 Studies on women doing ART while actively testing COVID+

  • 6:51 Studies on women doing ART after recently testing COVID +

  • 18:05 Recap

Table Summary on Studies of Patients Doing IVF, ICSI and/or Frozen Embryo Transfer While Actively Testing Positive for COVID-19

Table Summary on Studies of Patients doing IVF and/or Embryo Transfer After Recently Testing Positive for COVID-19

Resources

Actively Testing COVID+

Boudry L, Essahib W, Mateizel I, et al. Undetectable viral RNA in follicular fluid, cumulus cells, and endometrial tissue samples in SARS-CoV-2-positive women. Fertil Steril. 2022;117(4):771-780. doi:10.1016/j.fertnstert.2021.12.032

Clain E, Johnson J, Roeca C. Triggered with COVID: What are my chances, Doc?. Fertil Steril. 2022;117(4):781-782. doi.org/10.1016/j.fertnstert.2022.01.039

Demirel C, Tulek F, Celik HG, Donmez E, Tuysuz G, Gökcan B. Failure to Detect Viral RNA in Follicular Fluid Aspirates from a SARS-CoV-2-Positive Woman. Reprod Sci. 2021;28(8):2144-2146. doi:10.1007/s43032-021-00502-9

Kteily K, Pening D, Diaz Vidal P, et al. Risk of contamination of semen, vaginal secretions, follicular fluid and ovarian medulla with SARS-CoV-2 in patients undergoing ART. Hum Reprod. 2022;37(2):235-241. doi:10.1093/humrep/deab255

Recently Tested COVID+

Aizer A, Noach-Hirsh M, Dratviman-Storobinsky O, et al. The effect of coronavirus disease 2019 immunity on frozen-thawed embryo transfer cycles outcome. Fertil Steril. 2022;117(5):974-979. doi:10.1016/j.fertnstert.2022.01.009

Herrero Y, Pascuali N, Velázquez C, et al. SARS-CoV-2 infection negatively affects ovarian function in ART patients. Biochim Biophys Acta Mol Basis Dis. 2022;1868(1):166295. doi:10.1016/j.bbadis.2021.166295

Orvieto R, Segev-Zahav A, Aizer A. Does COVID-19 infection influence patients' performance during IVF-ET cycle?: an observational study. Gynecol Endocrinol. 2021;37(10):895-897. doi:10.1080/09513590.2021.1918080

Wang M, Yang Q, Ren X, et al. Investigating the impact of asymptomatic or mild SARS-CoV-2 infection on female fertility and in vitro fertilization outcomes: A retrospective cohort study. EClinicalMedicine. 2021;38:101013. doi:10.1016/j.eclinm.2021.101013

Yossef KB, Bentov Y, Gil M, et al. IVF and Early Pregnancy Outcome in Recent COVID 19 Recoverees., 30 November 2021, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-1055952/v1] preprint, not peer-reviewed

Youngster M, Avraham S, Yaakov O, et al. The impact of past COVID-19 infection on pregnancy rates in frozen embryo transfer cycles [published online ahead of print, 2022 May 7]. J Assist Reprod Genet. 2022;1-6. doi:10.1007/s10815-022-02517-w

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